Hobbies:
Chemistry, Gym
Education:
2024.07-present Nankai University, College of Chemistry, Prof. Shou-Fei Zhu's Research Group, Postdoctor
2019.03-2024.03, Moffitt Cancer Center & Research Institute, Post-Doc, Supervisor: Prof. Justin, M Lopchuk.
2013.09-2018.12, Nankai University, PhD, Supervisor: Prof. Qi-Lin Zhou
2009.08-2013.06, Lanzhou University, Bachelor Degree, Supervisor: Prof. Peng-Fei Xu
Self-Introduction:
My name is Wen Che. It’s my pleasure to be back in Prof. Zhu’s group. I hope I can devote my intelligence and strength to the development of new and useful reactions in the future.
Papers:
1. Che, W.; Wen, D. C.; Zhu, S.-F.; Zhou, Q.-L. Iterative Synthesis of Polydeoxypropionates Based on Iridium-Catalyzed Asymmetric Hydrogenation of α-Substituted Acrylic Acids. Org. Lett. 2018, 20, 3305-3309.
2. Che, W.; Li, Y.-Z.; Liu, J.-C.; Zhu, S.-F.; Xie, J.-H.; Zhou, Q.-L. Stereodiverse Iterative Synthesis of 1,3-Polyol Arrays through Asymmetric Catalytic Hydrogenation. Formal Total Synthesis of (−)-Cyanolide A. Org. Lett. 2019, 21, 2369-2373.
3. Che, W.; Wen, D. C.; Zhu, S.-F.; Zhou, Q.-L. Enantioselective Total Synthesis of (−)-Doliculide Using Catalytic Asymmetric Hydrogenations. Helv. Chim. Acta 2019, 102, e1900023.
4. Che, W; Wojtas, L.; Shan, C.; Lopchuk, J. M. Divergent synthesis of complex withanolides enabled by a scalable route and late-stage functionalization. Sci.Adv. 2024, in press.
5. Liu, Y.; Cheng, L.-J.; Yue, H.-T.; Che, W.; Xie, J.-H.; Zhou, Q.-L. Divergent enantioselective synthesis of hapalindole-type alkaloids using catalytic asymmetric hydrogenation of a ketone to construct the chiral core structure. Chem. Sci. 2016, 7, 4725-4729.
6. Yang, S.; Che, W.; Wu, H.-L.; Zhu, S.-F.; Zhou, Q.-L. Neutral iridium catalysts with chiral phosphine-carboxy ligands for asymmetric hydrogenation of unsaturated carboxylic acids. Chem. Sci. 2017, 8, 1977-1980.
7. Maharaj, V.; Chandrachud, P. P.; Che, W.; Wojtas, L.; Lopchuk, J. M. Photodecarboxylative Amination of Redox-Active Esters with Diazirines. Org. Lett. 2021, 23, 8838-8842.
